Table 1.
Patient cohort; NSCLC = Non-Small Cell Lung Cancer, COPD = chronic obstructive pulmonary disease, MLD = mean lung dose, V20 calculation of the biological effective dose is based on α/β =4.
| SBPT patients | SBRT patients | |
|---|---|---|
| Median Age [IQR] | 70.6 [64–76] | 75.8 [71–80] |
| Sex | ||
| Male | 6 | 7 |
| Female | 17 | 16 |
| Tumor Histology | ||
| Adenocarcinoma | 15 | 11 |
| Squamous Cell | 2 | 1 |
| Unspecified NSCLC | 6 | 11 |
| Lobe | ||
| Upper | 16 | 16 |
| Lower | 7 | 7 |
| Tumor Stage | ||
| T1a | 19 | 17 |
| T1b | 2 | 3 |
| T2a | 2 | 3 |
| Lung Disease | ||
| None | 8 | 10 |
| COPD, no home O2 | 9 | 10 |
| COPD, with home O2 | 6 | 3 |
| Current Smoker | ||
| Yes | 5 | 5 |
| No | 18 | 18 |
| Radiation Regimen | ||
| 48 Gy/4 fractions | 13 | 15 |
| 42 Gy/3 fractions | 3 | 0 |
| 48 Gy/3 fractions | 5 | 0 |
| 45 Gy/3 fractions | 1 | 0 |
| 50 Gy/5 fractions | 1 | 4 |
| 60 Gy/5 fractions | 0 | 3 |
| 45 Gy/5 fractions | 0 | 1 |
| Median MLD [IQR] | 2.0 Gy [1.7–2.8] | 2.6 Gy [1.8–3.4] |
| Median V20 [IQR] | 0.065 [0.06–0.09] | 0.062 [0.03–0.10] |