Table 5.
Level II (4.0 Gy/fx) (n=8) Grade |
Level III (4.5 Gy/fx) (n=7) Grade |
Level IV (5.0 Gy/fx) (n=8) Grade |
|||||||
---|---|---|---|---|---|---|---|---|---|
3 | 4 | 5 | 3 | 4 | 5 | 3 | 4 | 5 | |
Definitely, Probably, or Possibly Related to Protocol Treatment | |||||||||
Worst hematologic | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
Worst non-hematologic | 0 | 0 | 0 | 1 | 0 | 0 | 2 | 0 | 0 |
Worst overall | 0 | 0 | 0 | 2 | 0 | 0 | 2 | 0 | 0 |
Lymphopenia | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
Diarrhea | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 |
Large Bowel Obstruction* | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Enteritis | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 |
Colonic Hemorrhage* | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Hyperglycemia | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Any Relationship to Protocol Treatment | |||||||||
Worst hematologic | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
Worst non-hematologic | 1 | 0 | 0 | 1 | 1 | 0 | 2 | 0 | 0 |
Worst overall | 1‡ | 0 | 0 | 2 | 1† | 0 | 2 | 0 | 0 |
Abbreviations: Gy, Gray; fx, fraction
This was a patient with grade 3 ascites and encephalopathy unrelated to treatment.
This was a small intestinal stricture unlikely related to treatment.
This is the same patient.