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. Author manuscript; available in PMC: 2020 Jul 1.
Published in final edited form as: Am J Obstet Gynecol. 2019 Feb 23;221(1):48.e1–48.e18. doi: 10.1016/j.ajog.2019.02.040

Table 2:

Correlates of subfertility among women attending the safer conception cohort (n=182)

Univariate Multi variable Weight Adjusted MuInvariable
RR (95% Cl) p-Value RR (95%CI) p-Value RR (95%CI) p-Value
Individual & Partnership Characteristics
Female Age 1.03 (1.01–1.05) <0.01 1.03 (1.01–1.05) <0.01 1.03 (1.01–1.05) <0.01
Employment status
 Unemployed REF
 Employed 0.95 (0.75–1.19) 0.646
Age difference between partners
 <5 years REF REF REF
 > 5 years 0.81 (0.65–1.02) 0.072 0.86 (0.70–1.05) 0.149 0.87 (0.71–1.07) 0.177
Length of Relationship with Current partner
 0–2 years REF
 2 or more years 1.06 (0.82–1.39) 0.652
Clinical & Behavioral Characteristics
Female HIV status and HAART use
 HIV- REF REF REF
 HIV+, no HAART 2.01 (1.16–3.47) 0.012 2.00 (1.21–3.28) <0.01 2.00 (1.19–3.34) <0.01
 HIV+, HAART 0–2 years 1.63 (0.94–2.82) 0.080 1.76 (1.08–2.87) 0.024 1.89 (1.14–3.10) 0.013
 HIV+, HAART 2+ years 1.72 (1.00–2.93) 0.048 1.62 (0.99–2.65) 0.056 1.63 (0.98–2.69) 0.058
Male partner HIV status
 HIV- REF REF REF
 HIV+ 1.11 (0.86–1.44) 0.417 1.33 (1.04–1.71) 0.025 1.31 (1.02–1.68) 0.035
 Unknown 1.36 (0.93–1.99) 0.115 1.32 (0.87–2.00) 0.189 1.34 (0.91–1.98) 0.134
Weight in kg 1.00 (0.99–1.01) 0.903
Current or History of STI
 No REF
 Yes 1.04 (0.65–1.67) 0.875
Partner Smoker
 No REF REF REF
 Yes 1.27 (1.03–1.57) 0.028 1.31 (1.05–1.63) 0.015 1.29 (1.05–1.60) 0.017
Any alcohol consumption by partner
 No REF
 Yes 1.03 (0.81–1.30) 0.827
History of TB
 No REF
 Yes 1.07 (0.80–1.41) 0.656
Partner reported erectile dysfunction
 No REF
 Yes 0.68 (0.42–1.09) 0.109
Condomless sex acts per month 1.01 (0.97–1.06) 0.542
Accompanied by partner in clinic
 Unaccompanied REF
 Accompanied 0.95 (0.76–1.18) 0.621
Reproductive History
Number of live births
 Zero REF REF REF
 One 0.82 (0.65–1.03) 0.085 0.96 (0.77–1.21) 0.736 0.98 (0.77–1.24) 0.861
 Two or more 0.67 (0.51–0.90) <0.01 0.80 (0.60–1.07) 0.133 0.77 (0.57–1.03) 0.079
Previously been pregnant with current partner
 No REF REF REF
 Yes 0.80 (0.63–1.02) 0.072 0.92 (0.72–1.16) 0.472 0.91 (0.72–1.15) 0.431
a Reported history of abortion
 No REF
 Yes 1.14 (0.79–1.63) 0.484
a History of miscarriage
 No REF
 Yes 1.11 (0.85–1.45) 0.447
Age at Menarche 0.97 (0.92–1.03) 0.356
Flow days in Menstrual Cycle 1.02 (0.97–1.07) 0.448
Missed or irregular period in the past three months
 No REF REF REF
 Yes 1.10 (0.86–1.42) 0.447 1.20 (0.92–1.56) 0.182 1.17 (0.90–1.51) 0.240
Tried to conceive for at least one year and failed
 No REF REF REF
 Yes 1.49 (1.22–1.82) <0.001 1.42 (1.17–1.73) <0.01 1.38 (1.13–1.68) <0.01

HAART: highly active antiretroviral therapy, STI: sexually transmitted infection, TB: Turberculosis

Models estimated using robust Poisson regression. Weight adjusted multivariable models apply inverse probability weighting.

a

Among clients who have history of previous pregnancy (n=145)