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. Author manuscript; available in PMC: 2020 Jul 1.
Published in final edited form as: J Thorac Oncol. 2019 May 7;14(7):1184–1191. doi: 10.1016/j.jtho.2019.04.019

Table 2.

Estimated RR for lung cancer based on proband’s first degree family history, ignoring SDRs and TDRs

Number Affected FDRs Number Observed Expected RR 95% CI p-value
0 1,273,106 4,657 4,287.9 1.09 1.06, 1.12 <0.00001
>=1 42,781 751 292.2 2.57 2.39, 2.76 <0.00001
>=2 2,559 85 21.4 3.97 3.17, 4.90 <0.00001
>=3 175 6 1.4 4.24 1.56, 9.23 <0.00001

FDR – First Degree Relative; SDR – Second Degree Relative; TDR – Third Degree Relative