Table 7:

Exploratory higher dose (32 mg/kg) results for Magnitude (Magn) of amplitude and frequency tremor, Voice Handicap Index (VHI-10) and auditory-perceptual (A-P) tremor severity ratings: group means, standard deviations (SD), F-statistics and P values with and without baseline (BL) covariance adjustment (alpha <0.05). Means are for data from Baseline 3 and Post-test 3 for each drug phase.

	Magn of Amplitude Tremor Mean	SD	F value (with BL covariance)	P value (with BL covariance)	F value (without BL covariance)	P value (without BL covariance)
Octanoic acid
Baseline	12.73	6.74
Post-test	9.79	5.28
Placebo
Baseline	13.07	6.75
Post-test	12.98	8.24
Statistical Results			1.90	0.1934	3.69	0.0787
	Magn of Frequency Tremor Mean	SD	F value (with BL covariance)	P value (with BL covariance)	F value (without BL covariance)	P value (without BL covariance)
Octanoic acid
Baseline	5.68	3.90
Post-test	5.14	3.19
Placebo
Baseline	5.74	4.24
Post-test	5.64	3.73
Statistical Results			0.37	0.5530	0.28	0.6094
	VHI-10 Mean	SD	F value (with BL covariance)	P value (with BL covariance)	F value (without BL covariance)	P value (without BL covariance)
Octanoic acid
Baseline	16.33	7.44
Post-test	14.29	8.13
Placebo
Baseline	19.21	8.60
Post-test	15.79	7.64
Statistical Results			0.00	0.9831	0.01	.9323
	A-P Tremor Severity Mean	SD	F value	P value
Octanoic acid
Sustained vowel	1.79	1.31
All-voiced sentence	1.29	1.33
Placebo
Sustained vowel	1.57	1.45
All-voiced sentence	1.36	1.01
Statistical Results
Drug (Main effect)			0.03	0.8670
Task (Main effect)			1.84	0.1921
Drug*Task			0.20	0.6587