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. 2019 Jun 25;9:9251. doi: 10.1038/s41598-019-45461-z

Figure 3.

Figure 3

Time course of VLP specific antibody responses following quadrivalent vaccination via intradermal microneedle injection. Anti-VLP antibody levels at days 21 (A), 42 (B), 56 (C), 70 (D) and 84 (E) were determined by ELISA using serially diluted heat-inactivated sera from each of the individual pigs. The mean value and standard deviation is shown for triplicate samples for each dilution. Geometric mean antibody titres peaked at day 42 and were maintained through to day 84 (F).