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. 2019 Jun 25;9:9273. doi: 10.1038/s41598-019-45385-8

Table 1.

Metabolic pathways altered by a 100 dB SPL, 8–16 kHz 2 hr noise exposure.

Pathway P-value FDR
Alanine, aspartate and glutamate metabolism 0.00045298 0.021229
Purine metabolism 0.00051779 0.021229
Phenylalanine, tyrosine and tryptophan biosynthesis 0.00046167 0.018928
Phenylalanine metabolism 0.0040809 0.11154

The top 2 up-regulated (bold) and down-regulated (italic) metabolic pathways identified by the MetaboAnalyst webtool. P-value is calculated by a hypergeometric test. FDR = false discovery rate.