Table 2.
List of phenolic acids
| Phenolic acid name | Concentration | Cell line | Mechanisms | Reference |
|---|---|---|---|---|
|
Tatariside B Tatariside C Tatariside D |
18.3 μg/mL 6.44 μg/mL 2.83 μg/mL |
A549 | Inhibition of proliferation of cell line | [63] |
| 4-ACGC |
37.73 μg/mL 50.6 μg/mL 62.0 μg/mL |
A549 NCI-H1299 HCC827 |
Upregulation of caspase-3 & 9, Bad, and Bax down-regulation of Bcl-2 |
[64] |
| p-Coumaric acid | 50–100 μM | H1993 | Suppression of cell viability | [61] |
| 50–1000 μM | A549 | Decreased proliferation, superoxide anion production, cell adhesion, and cell migration | [66] | |
| Salicylic acid | 6.0 mM | A549 | Proapoptotic, antiproliferative, and cytotoxic effects | [68] |
| Gallic acid |
10–50 μM 100–200 μM |
Calu 6 A549 |
Depletion of glutathione and increasing ROS levels | [70] |
| 50 μM | H1975 | Inhibition of Src-mediated STAT3 phosphorylation, leading to downregulation of STAT3 target genes (Bcl2 and cyclin D) causing apoptosis and cell cycle arrest | [71] | |
| 5 μM | H1993 | Inhibition of Src-mediated STAT3 phosphorylation, leading to downregulation of STAT3 target genes (Bcl2 and cyclin D) causing apoptosis and cell cycle arrest | [61] | |
| Caffeic acid | 50–1000 μM | A549 | Decreased proliferation, superoxide anion production, cell adhesion, and cell migration | [66] |
| Ferulic acid | 50–1000 μM | A549 | Decreased proliferation, superoxide anion production, cell adhesion, and cell migration | [66] |