TABLE 2.
Minimum inhibitory concentration values for C. jejuni strains isolated from different sources against antimicrobial agents.
| Sources | Antibiotic | No. of sensitive strains/% | No. of resistant strains/% |
Antimicrobial agents MIC for C. jejuni isolates (MIC; μg/mL) |
||||||||||
| 0.25 | 0.5 | 1 | 2 | 4 | 8 | 16 | 32 | 64 | 128 | 256 | ||||
| Human cases (N = 101) | TET | 79/78.2 | 22/21.8 | 41/40.6 | 32/31.7 | 5/5.0 | 1/1.0 | 5/5.0 | 10/9.9 | 4/4.0 | 3/3.0 | |||
| ERY | 99/98.0 | 2/2.0 | 16/15.8 | 54/53.5 | 28/27.7 | 1/1.0 | 2/2.0 | |||||||
| CIP | 12/11.9 | 89/88.1 | 2/2.0 | 10/9.9 | 3/3.0 | 40/39.6 | 27/26.7 | 17/16.8 | 2/2.0 | |||||
| GEN | 101/100 | 0/0 | 21/20.8 | 69/68.3 | 8/7.9 | 3/3.0 | ||||||||
| AXO | 53/52.5 | 48/47.5 | 1/1.0 | 1/1.0 | 3/3.0 | 13/12.9 | 35/34.7 | 38/37.6 | 7/6.9 | 2/2.0 | 1/1.0 | |||
| Broiler products (N = 98) | TET | 35/35.7 | 63/64.3 | 13/13.3 | 6/6.1 | 6/6.1 | 7/7.1 | 3/3.1 | 11/11.2 | 25/25.5 | 9/9.2 | 11/11.2 | 7/7.1 | |
| ERY | 98/100 | 0/0 | 18/18.4 | 26/26.5 | 32/32.7 | 19/19.4 | 3/3.1 | |||||||
| CIP | 0/0 | 98/100 | 5/5.1 | 11/11.2 | 33/33.7 | 12/12.2 | 23/23.5 | 13/13.3 | 1/1.0 | |||||
| GEN | 98/100 | 0/0 | 36/36.7 | 41/41.8 | 20/20.4 | 1/1.0 | ||||||||
| AXO | 28/28.6 | 70/71.4 | 1/1.0 | 3/3.1 | 24/24.5 | 32/32.7 | 21/21.4 | 14/14.3 | 3/3.1 | |||||
| Dairy cattle (N = 41) | TET | 6/14.6 | 35/85.4 | 4/9.8 | 1/2.4 | 1/2.4 | 3/7.3 | 6/14.6 | 22/53.7 | 4/9.8 | ||||
| ERY | 41/100 | 0/0 | 1/2.4 | 11/26.8 | 15/36.6 | 7/17.1 | 5/12.2 | 1/2.4 | 1/2.4 | |||||
| CIP | 4/9.8 | 37/90.2 | 4/9.8 | 2/4.9 | 6/14.6 | 18/43.9 | 7/17.1 | 1/2.4 | 3/7.3 | |||||
| GEN | 41/100 | 0/0 | 18/43.9 | 21/51.2 | 2/4.9 | |||||||||
| AXO | 0/0 | 41/100 | 20/48.8 | 15/36.6 | 4/9.8 | 2/4.9 | ||||||||
| Wild birds (N = 101) | TET | 92/91.1 | 9/8.9 | 44/43.6 | 6/5.9 | 25/24.8 | 9/8.9 | 8/7.9 | 1/1.0 | 4/4.0 | 1/1.0 | 3/3.0 | ||
| ERY | 100/99.0 | 1/1.0 | 51/50.5 | 11/10.9 | 32/31.7 | 3/3.0 | 3/3.0 | 1/1.0 | ||||||
| CIP | 13/12.9 | 88/87.1 | 13/12.9 | 47/46.5 | 27/26.7 | 12/11.9 | 2/2.0 | |||||||
| GEN | 101/100 | 0/0 | 36/35.6 | 42/41.6 | 20/19.8 | 2/2.0 | 1/1.0 | |||||||
| AXO | 54/53.5 | 47/46.5 | 1/1.0 | 11/10.9 | 6/5.9 | 36/35.6 | 19/18.8 | 15/14.9 | 11/10.9 | 2/2.0 | ||||
| All sources (N = 341) | TET | 212/62.2 | 129/37.8 | 102/29.9 | 44/12.9 | 37/10.9 | 16/4.7 | 13/3.8 | 15/4.4 | 40/11.7 | 42/12.3 | 22/6.5 | 10/2.9 | |
| ERY | 338/99.1 | 3/0.9 | 70/20.5 | 64/18.8 | 133/39.0 | 57/16.7 | 12/3.5 | 1/0.3 | 1/0.3 | 3/0.9 | ||||
| CIP | 29/8.5 | 312/91.5 | 2/0.6 | 27/7.9 | 54/15.8 | 47/13.8 | 103/30.2 | 46/13.5 | 43/12.6 | 18/5.3 | 1/0.3 | |||
| GEN | 341/100 | 0/0 | 111/32.6 | 173/50.7 | 50/14.7 | 3/0.9 | 3/0.9 | 1/0.3 | ||||||
| AXO | 135/39.6 | 206/60.4 | 2/0.6 | 1/0.3 | 15/4.4 | 22/6.5 | 95/27.9 | 109/32.0 | 58/17.0 | 31/9.1 | 8/2.3 | |||
TET, tetracycline; ERY, erythromycin; CIP, ciprofloxacin; GEN, gentamicin; AXO, ceftriaxone; MIC, minimum inhibitory concentration.