Table 3.
Linear mixed model analysis: PDQ-SI as a function of potential clinical factors.
| Covariate | Multivariable analysis | ||
|---|---|---|---|
| Parameter Estimate | 95% CI | p-value | |
| Age in years | — | — | — |
| Age of onset in years | — | — | — |
| Age at diagnosis in years | — | — | — |
| Male gender | −0.374 | (−0.184, −0.565) | 0.000 |
| Unemployed status | — | — | — |
| Lower than GCE O level of education | — | — | — |
| Onset before age 50 | — | — | — |
| Disease duration in days | — | — | — |
| ECAQ score | — | — | — |
| 1-year follow-up visit | — | — | — |
| UPDRS IV total score | 0.671 | (0.129, 1.200) | 0.014 |
| LEDD in mg | — | — | — |
| NMSS total score | 0.305 | (0.257, 0.352) | 0.000 |
| H&Y staging (≥3) | 0.358 | (0.185, 0.637) | 0.012 |
| UPDRS III total score | 0.179 | (0.100, 0.258) | 0.000 |
| S&E ADL | — | — | — |
Abbreviation - ECAQ: Elderly Cognitive Assessment Questionnaire; UPDRS IV: Unified Parkinson’s Disease Rating Scale Part IV; LEDD: Levodopa Equivalent Daily Dose; NMSS: Non-Motor Symptoms Scale; H&Y: Hoehn and Yahr staging; UPDRS III: Unified Parkinson’s Disease Rating Scale Part III (motor); S&E ADL: Schwab and England Activities of Daily Living Scale.