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. 2019 Jun 19;9:529. doi: 10.3389/fonc.2019.00529

Table 1.

Patient and tumor characteristics at recurrence.

n %
CEA (ng/mL)
Median (range) 6.82 (0.20–109.28)
Histology
Adenocarcinoma 14 34.1
Mucinous ca 1 2.4
Not confirmed 26 63.4
Pattern of failure
Local only 24 58.5
Regional only 6 14.6
Locoregional 6 14.6
Local & distant 2 4.9
Regional & distant 1 2.4
Local, regional & distant 2 4.9
Tumor size (cm)
Median (range) 3.3 (1.5–11.0)
<3.3 cm 20 48.8
≥3.3 cm 21 51.2
Initial RT isodose line
<40 Gy 3 7.3
40–45 Gy 7 17.1
45–50 Gy 5 12.2
≥ 50 Gy 26 63.4
Guillem class
Axial 10 24.4
Anterior 8 19.5
Posterior 9 22
Lateral 8 19.5
Anterior & lateral 5 12.2
Posterior & lateral 1 2.4
rT stage
T0 6 14.6
T1 0 0
T2 0 0
T3 7 17.1
T4 28 68.3
rN stage
N0 29 70.7
N1 10 24.4
N2 2 4.9
R-stage
II 26 63.4
III 10 24.4
IV 5 12.2

CEA, carcinoembryonic antigen; RT, radiotherapy.