Table 1.
Survivor and control demographic and descriptive comparisons.
| Survivors n = 29 | Controls n = 29 | Group differences | Cohen's D | |
|---|---|---|---|---|
| Gender | 45% Female | 48% Female | ||
| Age at exam (years) |
M = 21.34 SD = 5.35 |
M = 22.43 SD = 5.20 |
t = 0.79, p = .56 | −0.02 |
| Years of education |
M = 13.28 SD = 2.79 |
M = 14.34 SD = 2.79 |
t = −1.77, p = .08 | −0.38 |
| Age at diagnosis (years) |
M = 8.55 SD = 4.88 Range 1–18 |
|||
| Radiation | n = 15 52% | |||
| Chemotherapy | n = 14 48% | |||
| High grade tumor | n = 14 48% | |||
| Hydrocephalus | n = 24 83% | |||
| Seizure medication | n = 1 3% | |||
| Hormone deficiency | n = 16 55% | |||
| Whole brain grey matter volume** |
M = 0.77 SD = 0.05 |
M = 0.81 SD = 0.02 |
t = 4.04, p < .01 | −1.05 |
| Whole brain white matter volume* |
M = 0.31 SD = 0.02 |
M = 0.32 SD = 0.02 |
t = 2.46, p = .02 | −0.50 |
| Right cerebellar volume |
M = 0.10 SD = 0.03 |
M = 0.10 SD = 0.05 |
t = 0.54, p = .59 | 0.00 |
| Right dentate volume |
M = 0.04 SD = 0.02 |
M = 0.04 SD = 0.03 |
t = 0.60, p = .55 | 0.00 |
| Left red nucleus volume |
M = 0.03 SD = 0.02 |
M = 0.04 SD = 0.03 |
t = 0.45, p = .65 | −0.39 |
| Left thalamus volume |
M = 0.04 SD = 0.02 |
M = 0.04 SD = 0.03 |
t = −0.05, p = .96 | 0.00 |
| Left frontal volume |
M = 0.07 SD = 0.02 |
M = 0.06 SD = 0.03 |
t = −0.67, p = .51 | 0.39 |
| Cerebellar-frontal FA |
M = 0.32 SD = 0.06 |
M = 0.32 SD = 0.05 |
t = −0.04, p = .97 | 0.00 |
| Cerebellar-frontal RD** |
M = 0.0013 SD = 0.0003 |
M = 0.0011 SD = 0.0001 |
t = −2.64, p < .01 | 0.89 |
Note. ** indicates p < .01 and * indicates p < .05; All volume measures are regional grey matter plus white matter divided by intracranial vault.