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Disruption of PPARα in hepatocytes results in decreased DNA repair gene expression after PHx. A–E: Quantitative PCR analysis of DNA repair–related gene Chek1, Mcm2/5, Prkdc, and Rad51 mRNAs at different time points after PHx. Data are expressed as means ± SD (A–E). n = 5 (A–E). ∗P < 0.05, ∗∗∗P < 0.001 versus Pparafl/fl.
