Figure 2.

Histopathology of tissues from C57BL/6 mice infected with Rickettsia parkeri by i.v. inoculation. A and B: Extensive mononuclear inflammatory cells around regions of hepatic coagulative necrosis. C: Lymphocytic infiltration in a portal triad. D: Scattered small lobular foci of inflammatory cell accumulations in hepatic lobules. E: Hepatic massive inflammatory infiltration surrounds areas of necrosis and perivascular locations at day 6 after infection, in mice infected with R. parkeri by i.v. inoculation. F: Perivascular-peribronchial inflammatory infiltration in lung of intravenously infected mice 6 days after infection. G: Foci of lymphocytic infiltration in perivascular area in lungs of intravenously infected mice 30 days after infection. H and I: Multiple lobular foci of mononuclear cell accumulations in the liver of convalescent mice 30 days after infection.