Table 2.

Brain regions with altered nodal parameters in T2DM patients.

AAL no.	Brain Regions		p-values
	Regions	Abbreviation	Nodal degree	Nodal efficiency	Nodal betweenness
T2DM <HC(14/26)
2	Right precentral gyrus	PreCG.R	0.052	0.034	0.036
3	Left superior frontal gyrus (dorsolateral)	SFGdor.L	0.519	0.196	0.005
20	Right supplementary motor area	SMA.R	0.141	0.156	0.044
23	Left superior frontal gyrus (medial)	SFGmed.L	0.335	0.183	0.012
33	Left median cingulate and paracingulate gyri	DCG.L	0.059	0.037	0.652
41	Left amygdala	AMYG.L	0.499	0.385	0.026
46	Right cuneus	CUN.R	0.054	0.039	0.652
47	Left lingual gyrus	LING.L	0.008	0.009	0.340
48	Right lingual gyrus	LING.R	0.008	0.012	0.531
49	Left superior occipital gyrus	SOG.L	0.004	0.010	0.135
50	Right superior occipital gyrus	SOG.R	0.016	0.017	0.656
51	Left middle occipital gyrus	MOG.L	0.058	0.045	0.010
52	Right middle occipital gyrus	MOG.R	0.039	0.015	0.047
63	Left supramarginal gyrus	SMG.L	0.058	0.037	0.024
T2DM>HC(12/26)
28	Right gyrus rectus	REC.R	0.048	0.034	0.252
32	Right anterior cingulate and paracingulate gyri	ACG.R	0.930	0.597	0.040
36	Right posterior cingulate gyrus	PCG.R	0.488	0.903	0.033
65	Left angular gyrus	ANG.L	0.865	0.552	0.040
71	Left caudate nucleus	CAU.L	0.001	0.004	0.005
72	Right caudate nucleus	CAU.R	0.030	0.030	0.084
91	Left cerebellum crus1	CRBLCrus1.L	0.150	0.374	0.049
92	Right cerebellum crus1	CRBLCrus1.R	0.182	0.504	0.025
95	Left cerebellum 3	CRBL3.L	0.010	0.011	0.532
96	Right cerebellum 3	CRBL3.R	0.004	0.001	0.208
109	Vermis (1, 2)	Vermis(1, 2)	0.015	0.140	0.616
110	Vermis 3	Vermis 3	0.003	0.141	0.023

AAL No., number of automated anatomical labeling. Note: Brain regions were considered abnormal in T2DM patients if they showed p < 0.05 compared to HCs in at least one of the three nodal parameters and boldface p-values were statistically significant.