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. 2019 Jun 6;9:200. doi: 10.3389/fcimb.2019.00200

Figure 3.

Figure 3

Simulated Ab binding occupancy, neutralization, and ADE in primary DENV infection using the smooth virus conformation. Estimated Ab binding occupancy (A), infectivity (B), and ADE (C) at a range of TS and CR Ab concentrations for highly mature (5% prM content), moderately mature (10% prM content), and low-maturity (30% prM content) virions during a primary or homotypic infection.