Table 1.

Lung morphometry.

	Control			Obese
	SAL	ALI	p	SAL	ALI	p
Collapse (%)	4.8 [2.9–5.5]	12.4 [9.7–19.2]	<0.0001	9.0 [6.1–10.5]*	18.8 [16.0–23.2]#	0.002
Interstitial edema	0.47 ± 0.25	0.94 ± 0.16	0.0002	0.89 ± 0.15*	0.80 ± 0.12	0.397
Neutrophils (%)	1.2 ± 0.6	5.7 ± 1.8	<0.0001	3.1 ± 0.6*	5.5 ± 1.6	0.001
Collagen fibers (%)	2.0 [1.7–2.9]	6.9 [5.8–7.5]	<0.0001	3.2 [2.1–4.1]	3.5 [3.1–3.9]#	0.43

Fraction area of collapsed alveoli, interstitial edema, percentage of neutrophils and collagen fibers in Control and Obese animals subjected to intratracheal instillation of saline (SAL) or endotoxin (ALI). Values represent median (interquartile range) or mean (SD) of nine animals/group. Interstitial edema represented as a dimensionless quantity.

^*vs. Control-SAL (p < 0.05);

^#vs. Control-ALI (p < 0.05).