Table 3.

Significantly differentially expressed miRNAs in DR serum samples in Chinese T2DM patients in previous studies.

Authors	Year	Region	Methods	MiRNA	Reported FC	This study FC
Liang et al., 2018	2018	Shenzhen	RNA-seq and qRT-PCR	hsa-let-7a-5p	↓	↓
				hsa-miR-28-3p	↓	↓
				hsa-miR-151a-5p	↑	↓*
				hsa-miR-148a-3p	↑	↑
Liu et al., 2018	2018	Shenyang	qRT-PCR	hsa-miR-221	↑	↑ (hsa-miR-221-3p)
Zou et al., 2017	2017	Nanjing	qRT-PCR	hsa-miR-93	↑	↑ (hsa-miR-93-5p)

↑ refers to up-regulated, ↓ refers to down-regulated. There was no statistical differences of these miRNAs in our study (p > 0.05). The latest mature miRNA names of the same mature form investigated in a previous study were provided in parentheses. The miRNA with inconsistent direction of fold change was highlight by asterisk. FC, fold change.