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. 2019 Jun 5;10:587. doi: 10.3389/fneur.2019.00587

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Copyright © 2019 Popa, Morris, Hunt, Deng, Horovitz, Mente, Shitara, Baek, Hallett and Voon.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effects of repetitive transcranial magnetic stimulation (rTMS) on intrinsic functional connectivity in healthy controls. Functional connectivity is schematically illustrated at baseline (i.e., pre-rTMS; top left) and post-rTMS (bottom left); pre- and post-rTMS effects on seed-to-seed functional connectivity are shown in the bar graphs. After rTMS, functional connectivity between mesial prefrontal cortex (mPFC) and ventral striatum (VS), and between mPFC and mid cingulate cortex (MCC) was reduced, while functional connectivity between MCC and VS was increased (the thickness of the arrows correspond to strength, and color to direction: red, positive connectivity; blue, negative connectivity). Error bars are shown as standard error of the mean. *p < 0.05, **p = 0.001.