Table 4.

Univariable and multivariable correlates of mechanical dispersion in aortic stenosis

Variables	Univariable analysis			Multivariable analysis
	β	95% CI	P-value	β	95% CI	P-value
Age (years)	0.47	0.34 to 0.61	<0.001	0.28	0.15 to 0.42	0.003
Sex (female)	−0.70	−4.32 to 2.92	0.704
Diabetes mellitus	3.16	−1.58 to 7.90	0.191
Arterial hypertension	2.50	−1.15 to 6.15	0.179
Previous myocardial infarction	9.87	4.59 to 15.15	<0.001	4.36	−0.63 to 9.34	0.087
Dyslipidaemia	−0.36	−4.46 to 3.75	0.865
History of atrial fibrillation	2.05	−3.78 to 7.88	0.490
Beta-blockers	2.15	−1.63 to 5.93	0.265
RAAS-inhibitors	2.08	−1.66 to 5.82	0.275
Calcium blockers	2.93	−1.50 to 7.36	0.195
Diuretics	6.26	2.27 to 10.24	0.002	3.65	−0.03 to 7.262	0.058
Statins	4.12	0.39 to 7.85	0.031	2.42	−0.96 to 5.80	0.160
LVEF (%)	−0.77	−0.93 to −0.61	<0.001	−0.24	−0.44 to −0.04	0.020
LV mass index (g/m2)	0.25	0.20 to 0.29	<0.001	0.20	0.15 to 0.26	<0.001
Aortic valve area (cm2)	−19.12	−23.20 to −15.04	<0.001	−8.55	−13.39 to −3.72	0.001
Stroke volume index (mL/m2)	−0.35	−0.49 to −0.19	<0.001	−0.03	−0.19 to 0.13	0.734
QRS-duration (per 10 ms)	3.24	2.35 to 4.14	<0.001	1.12	0.25 to 1.99	0.012

Bold are those with a P<0.05 (significant).

CI, confidence interval; EF, ejection fraction; LV, left ventricular; RAAS, renin–angiotensin–aldosterone system.