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Knockdown of SOX4 inhibits tumor formation and lung metastasis. (A) Tumor endpoint volumes, at 6 weeks postinjection in male BALB/c mice, of VCaP cells transduced with either shNC or shSOX4 (n= 5 per group). (B) Knockdown of SOX4 inhibits lung metastasis. Representative H&E images and the percentage of lung metastasis are shown.
