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. 2019 Jun 19;10:676. doi: 10.3389/fphar.2019.00676

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Copyright © 2019 Ye, Xue, Liu, Zhu, Li, Liu, Cai, Rui and Zhang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Activation of autophagy regulated antioxidant capacity. Cells were divided into six groups and treated for 48 h as described in the Figure 3 caption. (A) Monodansylcadaverine (MDC) staining assay was applied to detect autophagy. (B, C) The expression of autophagy and apoptosis related proteins in the different groups. (D) The fluorescence intensity of ROS. (E, F) The levels of MDA and SOD were analyzed using a microplate reader. The results are shown as mean ± SD (n = 3) and calculated from at least three independent experiments. ***P < 0.001, **P < 0.01, *P < 0.05, compared to the control group. ^### P < 0.001, compared to the DB group.