Table 6.

Some human and animal studied on the orange‐fleshed sweet potato (OFSP) in vitamin A‐related disease management

S. no.	Country/target group	Study	Results	Reference
1	Mozambique/Children	Longitudinal study reported from three deliberately selected districts, two are selected for intervention and one as control. Information was collected on demographic, agricultural, and anthropological issues. Blood samples were collected from all respondents for biochemical analysis	Intervention children reported higher intake of OFSP, reported high VA. Mean serum retinol level increased by 0.100 mM in intervention children, which are not increased in control subjects	Low et al. (2007)
2	Uganda/Children and women	Study was conducted to know impact of the intensive (IP) and reduced practices (RP) with a control on OFSP and VA intakes among children aged 6−35 months and 3–5 years and women, and IP compared with control on VA status of 3‐ to 5‐year‐old children and women with serum retinol <1.05 mM at baseline	9.5% point reduction in prevalence of serum retinol <1.05 mM identified. At follow‐up, VA intake from OFSP was correlated with VA status. Use of OFSP increased VA intakes of children and women	Hotz, Loechl, Lubowa, et al. (2012)
3	Bangladesh/women	Daily consumption of OFSP with or without added fat, on the VA status of Bangladeshi women with low initial VA status was done. Women received one of the following for 6 days/week over 10 weeks. 1. 10 mg RAE/day (WFSP and a corn oil) 2. 600 mg RAE/day (OFSP and a corn oil) 3. Fried OFSP and a corn oil capsule 4. Boiled WFSP and a retinyl palmitate capsule in addition to their home diets. Retinol and BC and VA were assessed before and after the 60 days	BC concentrations in plasma found in this study were high in groups consumed OFSP and plasma BC was higher in the consumed fried OFSP compared with boiled OFSP. Initial and final total body VA pool sizes were 0.060–0.047 mmol and 0.091–0.070 mmol. Concluded that, the impact of OFSP on VA status in Bangladeshi women was marginal	Jamil et al. (2012)
4	Mozambique/general consumers	Reported study on OFSP consumption. The two intervention models were compared: 1. Low intensity (1 year) 2. High‐intensity (nearly 3 years) training model	OFSP consumption raised VA among consumers. OFSP accounted for 47%–60% of all SP consummation provided 80% of total VA	Hotz, Loechl, de Brauw, et al. (2012)
5	South Africa/school children	Effect of boiled and mashed OFSP in improving VA levels in school children studied. Dewarmed 5–10 years kids were randomly assigned to following two sections for 53 days. 1. Treatment group consumed 125 g boiled and mashed OFSP 2. Control group given same portion of WFSP	High amount of VA reported in OFSP consumed group than control. The proportions of children with normal VA status in the treatment group increased and did not change in the control group	Van Jaarsveld et al. (2005)
6	Mozambique/children	Health benefits of biofortification in reducing VAD reported in rural area of north Mozambique	Children <5 years, biofortification reduced diarrhea prevalence by 11.4% and by 18.9% in children <3 years	Jones and de Brauw (2015)
7	Kenya/women	Role of OFSP nutrition and health‐promoting activity reported. VA intakes were assessed with multipass 24‐hr recalls in a subsample of 206 mothers at 8–10 months postpartum	22.9% of women had VA <1.17 mM. By 9 months of postpartum, intervention women had significantly higher intakes of VA‐rich OFSP in the previous 7 days	Girard et al. (2017)