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. 2019 Jun 25;10(3):e00188-19. doi: 10.1128/mBio.00188-19

TABLE 3.

Panobinostat EC50 values for each virusa

Strain EC50 (nM) 95% confidence interval P value
WT 1.603 1.118 to 2.299
M1 1.68 1.204 to 2.344 0.864
M2 2.972 2.226 to 3.969 0.11
ERK 12.86 11.01 to 15.03 0.0084
a

Panobinostat EC50 levels for each virus were determined as described in Fig. 5. There were no significant differences in the EC50 values for the M1 mutant. There was a small but nonsignificant difference in the EC50 level for the M2 mutant. The ERK mutant required a significantly higher concentration of panobinostat.