Table 2.
Classification of congenital heart disease (CHD) according to expected cerebral arterial oxygen saturation in study population of 181 fetuses
| Type of CHD | n |
|---|---|
| Expected normal cerebral arterial oxygen saturation | 44 |
| AVSD (1 with left isomerism, 1 with ASD) | 10 |
| Isolated VSD/VSDs | 13 |
| VSD + ASD (1 with absent ductus venosus) | 2 |
| Moderate AS (1 with PS) | 2 |
| CoA | 6 |
| PS and dysplastic pulmonary valve | 5 |
| Tricuspid valve abnormalities (antegrade flow over aortic arch) | 2 |
| Double discordance with Ebstein's anomaly (antegrade flow over aortic arch) | 1 |
| Mitral stenosis including small LV (antegrade flow over aortic arch) | 3 |
| Expected mild to moderately reduced cerebral arterial oxygen saturation | 84 |
| AS (critical, retrograde flow over aortic arch) | 1 |
| CoA with VSD (with or without AS or hypoplastic aortic arch) | 10 |
| Interrupted aortic arch with VSD | 2 |
| Ebstein's anomaly (retrograde flow in arterial duct (with or without PS/PA)) (1 with small VSD) | 5 |
| PS with VSD (n = 1)/tetralogy of Fallot (n = 14)/DORV with PS (n = 4) | 19 |
| PA with VSD | 4 |
| Atrioventricular discordance with DORV and CoA | 1 |
| Atrioventricular concordance with mal/transposed great arteries and PS | 4 |
| Atrioventricular concordance with mal/transposed great arteries and/or mitral hypoplasia and/or CoA, no PS or Taussig–Bing | 4 |
| Transposition of the great arteries with PS and mitral stenosis | 1 |
| Common arterial trunk (1 with AVSD) | 7 |
| PA with IVS | 5 |
| TA (with or without mal/transposition of the great arteries, hypoplastic aortic arch, PS or DORV) (1 with infracardiac TAPVD) | 7 |
| Hypoplastic right heart (TA or tricuspid stenosis with PA or critical PS with IVS) | 6 |
| Double inlet left ventricle (with or without mal/transposition of the great arteries with hypoplastic aortic arch or PA) (1 with AVSD and right isomerism) | 7 |
| Complex: right atrial isomerism with unbalanced AVSD, criss‐cross atrioventricular junction, PA with solitary outlet (Ao) from RV and PAPVC | 1 |
| Expected severely reduced cerebral arterial oxygen saturation | 53 |
| HLHS (aortic atresia with or without mitral atresia/stenosis) | 16 |
| Transposition of the great arteries with VSD | 10 |
| DORV with transposition of the great arteries (Taussig–Bing) with or without hypoplastic aortic arch | 3 |
| Transposition of the great arteries with IVS | 24 |
AS, aortic stenosis; ASD, atrial septal defect; AVSD, atrioventricular septal defect; CoA, coarctation of the aorta; DORV, double outlet right ventricle; HLHS, hypoplastic left heart syndrome; IVS, intact ventricular septum; LV, left ventricle; PA, pulmonary atresia; PAPVC, partial anomalous pulmonary venous connection; PS, pulmonary stenosis; RV, right ventricle; TA, tricuspid atresia; TAPVD, total anomalous pulmonary venous drainage; VSD, ventricular septal defect.