Figure 1.

Distribution of allelic imbalance (AI) events in articular cartilage. AI is reported as the average fraction (φ) of the alternative allele reads among the total number of reads. A, AI was defined for 13,853 called variants after selecting for at least 2 heterozygotes, selecting single‐nucleotide polymorphisms (SNPs) present in only single genes and removing low counts. B, After filtering by allelic fraction (0.1<φ<0.9) and meta false discovery rate <0.05, 2,070 SNPs remained that marked significant AI of 1,031 unique genes.