Figure 1.

TREM‐1 was part of physiological response to lipotoxicity in NAFLD. A, qRT‐PCR analysis of TREM‐1 in the livers of HFD‐fed vs NCD‐fed mice. B, Immunohistochemistry analysis of TREM‐1 in the livers of HFD‐fed vs NCD‐fed mice. C, Western blot analysis of TREM‐1 in the OA‐induced HepG2/PMH vs control cells. ***P < 0.001. GAPDH, glyceraldehyde 3‐phosphate dehydrogenase; HFD, high‐fat diet; NAFLD, nonalcoholic fatty liver disease; NCD, normal control diet; OA, oleic acid; PMH, primary mouse hepatocytes; qRT‐PCR, quantitative reverse‐transcription polymerase chain reaction; TREM‐1, triggering receptor expressed on myeloid cells‐1