Table 3.
Baseline parameters of cerebral microangiopathy and capillary perfusion
Cerebral microangiopathy | Type 1 diabetes (n = 25) | Controls (n = 25) | P‐value |
---|---|---|---|
CMB (n(%))—present yes/no | 5 (20.0%) | 4 (17.4%) | 0.941 |
WML (n(%))—present yes/no | 6 (24.0%) | 6 (24.0%) | 0.999 |
Skin capillary densitya | Type 1 diabetes (n = 17) | Controls (n = 20) | |
---|---|---|---|
Baseline perfusion (n/mm²) | 45.0 ± 7.7 | 50.6 ± 11.1 | 0.087 |
Peak perfusion (n/mm²) | 63.7 ± 13.6 | 70.4 ± 19.2 | 0.238 |
Venous occlusion (n/mm²) | 65.2 ± 13.3 | 70.6 ± 18.9 | 0.334 |
Capillary recruitment (absolute values) | 18.6 ± 7.9 | 19.7 ± 11.3 | 0.745 |
Capillary recruitment (%) | 40.7 ± 16.1 | 38.4 ± 17.6 | 0.685 |
Data are presented as mean ± SD or number (percentage). CMB, cerebral microbleeds; CR, capillary recruitment (ie, increase of capillaries in n/mm² from baseline to peak perfusion); WML, white matter lesions.
13 out of 50 perfusion measurements were excluded based on improper quality of the video microscopy image.