Table 1.
OKS and predicted utility scores (EQ-5D)a: used to model CRFA and IAS in primary analysis
| Baselineb | Month 1 | Month 3 | Month 6 | Month 12 | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| CRFA | IAS | CRFA | IAS | CRFA | IAS | CRFA | IAS | CRFA | IAS | ||
| OKS | Mean (SD) | 16.7 (4.4) | 16.9 (5.1) | 33.3 (9.2) | 29.4 (8.5) | 34.6 (8.3) | 24.6 (7.6) | 35.7 (8.8) | 22.4 (8.5) | 34.3 (11.1) | 22.0 (16.6) |
| Sample sizec | 76 | 75 | 67 | 69 | 65 | 68 | 58 | 67 | 52 | 3 | |
| SE | 0.50 | 0.59 | 1.13 | 1.03 | 1.02 | 0.93 | 1.16 | 1.04 | 1.54 | 9.61 | |
| Mapped EQ-5D | Mean (SE) | 0.335 (0.029) | 0.340 (0.030) | 0.708 (0.033) | 0.619 (0.031) | 0.735 (0.032) | 0.512 (0.030) | 0.761 (0.035) | 0.463 (0.032) | 0.729 (0.042) | 0.453 (0.238) |
Abbreviations: CRFA cooled radiofrequency ablation, IAS intra-articular steroid, OKS Oxford Knee Score, SD standard deviation, SE standard error
aIncludes all available observations
bTime points as per clinical trial NCT02343003
cSample size represents subjects with available data at each time point. Based on full analysis set from clinical trial NCT02343003