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. 2019 Jun 25;38:278. doi: 10.1186/s13046-019-1254-4

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Validation of MYOSLID expression in OSCC specimens and cell lines. a RT-qPCR validation of MYOSLID expression in 15 paired OSCC tissues and adjacent normal mucosa; a simple t test was used to test the significance of the differences between the 2 groups, p < 0.05. b Survival analysis of MYOSLID expression in an HNSCC microarray assay, p < 0.05. c MYOSLID expression in 4 OSCC cell lines. d siRNA sequences targeting the MYOSLID sequence. e Effect of silencing MYOSLID on the mRNA expression levels of p-EMT-related markers. f-g Classical EMT marker and p-EMT marker protein levels in 4 OSCC cell lines. siRNA-1 refers to MYOSLID-homo-96, and siRNA-2 refers to MYOSLID-homo-323