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. 2019 Jun 21;2(6):e195776. doi: 10.1001/jamanetworkopen.2019.5776

Table 2. Participant Characteristics for 5 Phases of Whitehall II Study.

Characteristic Phase 3, 1991-1994 Phase 5, 1997-1999 Phase 7, 2002-2004 Phase 9, 2007-2009 Phase 11, 2011-2013
Total participants 116 106 109 108 116
FRS %, median (IQR) [range]a 6.92 (4.65-10.22) [0.88-24.68] 8.99 (5.76-14.84) [1.17-32.33] 12.80 (9.01-18.18) [1.43-41.91] 15.55 (9.63-21.21) [3.06-58.00] 16.39 (11.44-24.59) [2.85-55.08]
FRS, No. (%)b
Low 86 (74.1) 58 (54.7) 36 (33.3) 30 (27.8) 16 (13.8)
Moderate 24 (20.7) 39 (36.8) 52 (47.7) 48 (44.4) 58 (50.0)
High 6 (5.2) 9 (8.5) 21 (19.3) 30 (27.8) 42 (36.2)
Age, mean (SD) [range], y 47.1 (5.0) [40.1-58.9] 52.9 (4.9) [45.7-64.8] 58.5 (5.0) [51.4-70.1] 63.5 (5.0) [56.4-75.3] 67.4 (4.9) [60.5-79.5]

Abbreviations: FRS, Framingham Risk Score; IQR, interquartile range.

a

Framingham Risk Score is expressed as a percentage of 10-year risk of cardiovascular disease.

b

Low risk defined as FRS less than or equal to 10%; moderate risk, FRS between 10% and 20%; and high risk, FRS greater than or equal to 20%.