Table 2. Estimated Regression Coefficients From Linear Mixed Models for Memory Change (SD Units) per Decade, Health and Retirement Study, United States, 1998-2014.
| Characteristic | β (95% CI)a | |||
|---|---|---|---|---|
| Model 0 | Model 1b | Model 2c | ||
| Participants who remained cancer free | ||||
| Memory slope with linear age | −1.115 (−1.127 to −1.104) | −1.116 (−1.126 to −1.105) | −1.102 (−1.113 to −1.091) | |
| Memory slope with quadratic age | −0.309 (−0.314 to −0.303) | −0.295 (−0.300 to −0.290) | −0.301 (−0.306 to −0.296) | |
| Difference for people diagnosed with cancer | ||||
| Precancer memory slope (linear) | 0.075 (0.037 to 0.113) | 0.091 (0.056 to 0.126) | 0.084 (0.049 to 0.119) | |
| Postcancer memory slope (linear) | 0.058 (0.013 to 0.102) | 0.071 (0.028 to 0.113) | 0.055 (0.012 to 0.097) | |
| Change in memory at the time of diagnosis | −0.056 (−0.081 to −0.297) | −0.057 (−0.082 to −0.030) | −0.058 (−0.084 to −0.032) | |
a
β values are regression coefficients for memory change per decade before and after diagnosis and at the time of diagnosis among participants with cancer compared with memory change per decade among those who remained cancer free throughout follow-up. Two-sided P < .01 for all comparisons.
b
Adjusted for sex, race, and Southern birthplace.
c
Adjusted for sex, race, Southern birthplace, childhood socioeconomic status, length of education, baseline household wealth, childhood self-rated health, alcohol use, current smoking, body mass index, baseline history of hypertension, diabetes, heart disease, stroke, lung disease, and arthritis.