Figure 7.

Voxelwise DTI and DTBM analysis of ferret brains. Brains from ferrets not infected with Zika virus were used to generate study specific DTI templates (a) and individual brain DTI volumes from Zika infected litters were warped to the template in order to calculate voxelwise effect size maps of local volume change (LogJ, b), diffusivity (trace, c), and anisotropy (FA, d). Cohen's D maps for LogJ—A morphometric measure—Showed prominent neocortical regions of decreased local volume for the Zika infected brains. This is especially evident by negative Cohen's D values (green color) in b