Figure 12.

Dimension of the VZ and SVZ in control, and Zika treated tissue. (a) (control) and (b) (Zika treated) shows the extent of the ventricular zone (VZ) and the inner (SVZi) and outer (SVZo) ventricular zones in the P0 ferret. The SVZi in the Zika treated animal is less distinct than that in the normal animal. These sections are immunoreacted with SOX2, a transcription factor, which reveals neural progenitor cells. (c) Shows the measurements of each region taken for three animals in each group. This illustrates that the overall dimension of the VZ and SVZ (SVZi +SVZo) was diminished in the Zika treated animals as well as the specific dimension of the SVZo (ANOVA followed by a Tukey multiple comparison test). **** p < 0.0001; ** p < 0.001