Figure 2.

Graft function during MP and reperfusion. (A) OER was greater at higher temperatures during MP, reflecting an increased graft metabolic rate. (B) During reperfusion, oxygen consumption was highest for livers preserved by MPRT. (C) Lactate levels in the perfusate decreased to low levels for all groups during MP. (D) During reperfusion, lactate levels trended lower for MPRT and SCS groups but did not reach significance. (E) Bile production during MP was proportional to temperature and metabolic rate. During reperfusion, bile production was greatest for livers that had been preserved by MPRT. (F) Biliary glucose levels during MP were lowest for MP37, indicating greater reabsorption by the biliary epithelium. During reperfusion, there was a trend toward lower biliary glucose in the MPRT group (P = 0.06, MPRT versus MP30). Data are shown as mean ± SEM, n = 6 per group. *P < 0.05, **P < 0.01, ***P < 0.001.