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. 2019 Jun 21;12:4883–4895. doi: 10.2147/OTT.S208830

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© 2019 Yuan et al.

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LINC01089 inhibits Wnt/β-catenin signaling.

Notes: (A) The levels of total β-catenin, active β-catenin, and several downstream target proteins were decreased upon ectopic expression of LINC01089. RT-qPCR revealed significantly reduced expression of CTNNB1 (B), CCND1 (C) and MYC (D) mRNA upon LINC01089 overexpression. Mean ± SD, n=3, *P<0.05, **P<0.01, and ***P<0.001.

Abbreviation: RT-qPCR, quantitative real-time polymerase chain reaction.