Figure 4.

Changes in carotid blood flow, cerebral oxygenation (cTOI), cerebral fractional tissue oxygen fraction (cFTOE) and pulse‐oximetry saturation (SpO2) in SF‐deficient newborn piglets treated with SF administered by the INSURE method or LISA using a nasogastric tube (NT) or LISAcath®. Cerebral effect on carotid blood flow (A), cTOI (B), cFTOE (C) and SpO2 (D) values; SF administration interval effect on carotid blood flow (Aa), cTOI (Bb), cFTOE (Cc) and SpO2 (Dd) values in the INSURE (black square), LISA‐NT (white square) and LISAcath® (white circle) groups. (*)P < 0.05 versus INSURE group (one‐way ANOVA); (#)P < 0.05 versus −2 min time point (Wilcoxon non‐parametric test). Values are mean ± SD. BAL, bronchoalveolar lavage; ST, stabilization