Figure 5.

Analysis of FOXA2 binding intervals in ERA genes. A) Venn diagrams comparing unique or common nonredundant genes with an associated FOXA2 binding interval in the proliferative (P)- and mid-secretory (MS)-phase endometrium based on RNA-Seq and overlap with ERA genes. Hypergeometric P values of overrepresentation of ERA genes with genes expressed in the specific phase or common to both the phases are shown. B) MI and centrality analysis of 28 transcription factors expressed in MS endometrium that have binding motifs in FOXA2 binding intervals associated with ERA genes determined by HOMER motif analysis of ChIP-Seq data. The top key players are highlighted in yellow.