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. 2019 Mar 28;33(7):8211–8220. doi: 10.1096/fj.201900015RR

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This is an Open Access article distributed under the terms of the Creative Commons Attribution 4.0 International (CC BY 4.0) (http://creativecommons.org/licenses/by/4.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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A) GO analysis of the differentially expressed proteins following 8 h exposure of placental villous fragments to TC vs. controls showed significant enrichment for GO terms related to metabolism, cell death, oxidative stress, and vesicle-mediated transport. The dotted line indicates a value of P = 0.05. B) Differentially expressed proteins that map to significant pathways (cellular response to oxidative stress, cell death, and vesicle-mediated transport) presented in heatmap format representing the ratio of expression in treated vs. control samples for each placenta.