TABLE 5.
Gene transcripts differentially expressed between hPOSTN-001 and control cells
| Gene symbol | Gene name | P | FDR | Fold change |
|---|---|---|---|---|
| Gene transcripts elevated in hPOSTN-001 cells compared with control cells | ||||
| MOV10L1 | Mov10 RISC complex RNA helicase–like 1 | <0.001 | <0.001 | 90.80 |
| GJB2 | Gap junction protein β 2 | <0.001 | <0.001 | 60.18 |
| LRP1B | LDL receptor related protein 1B | <0.001 | <0.001 | 42.41 |
| HSD17B3 | Hydroxysteroid 17-β dehydrogenase 3 | <0.001 | <0.001 | 36.43 |
| ZIC3 | Zic family member 3 | <0.001 | <0.001 | 24.05 |
| DCLK1 | Doublecortin-like kinase 1 | <0.001 | <0.001 | 12.20 |
| APCDD1 | APC down-regulated 1 | <0.001 | <0.001 | 10.57 |
| RSPO3 | R-spondin 3 | <0.001 | <0.001 | 10.47 |
| CTNNA3 | Catenin α 3 | <0.001 | <0.001 | 10.09 |
| DACH2 | Dachshund family transcription factor 2 | <0.001 | <0.001 | 9.84 |
| MPZL2 | Myelin protein zero-like 2 | <0.001 | <0.001 | 9.48 |
| CMKLR1 | Chemerin chemokine-like receptor 1 | <0.001 | <0.001 | 9.17 |
| APLNR | Apelin receptor | <0.001 | <0.001 | 8.99 |
| TRPM3 | Transient receptor potential cation channel subfamily M member 3 | <0.001 | <0.001 | 8.81 |
| LRRC17 | Leucine-rich repeat containing 17 | <0.001 | <0.001 | 7.22 |
| SYT4 | Synaptotagmin 4 | <0.001 | <0.001 | 7.17 |
| SOX21 | SRY-box 21 | <0.001 | <0.001 | 7.07 |
| PCSK2 | Proprotein convertase subtilisin/kexin type 2 | <0.001 | <0.001 | 6.83 |
| PCDH10 | Protocadherin 10 | <0.001 | <0.001 | 6.50 |
| HS3ST1 | Heparan sulfate-glucosamine 3-sulfotransferase 1 | <0.001 | <0.001 | 6.18 |
| Gene transcripts repressed in hPOSTN-001 cells compared with control cells | ||||
| PCDHB5 | Protocadherin β 5 | <0.001 | <0.001 | −667.80 |
| MARCKS | Myristoylated alanine-rich PKC substrate | <0.001 | <0.001 | −464.80 |
| TSPYL5 | TSPY-like 5 | <0.001 | <0.001 | −461.22 |
| HIST1H2BE | Histone cluster 1 H2B family member e | <0.001 | <0.001 | −423.59 |
| PARVA | Parvin α | <0.001 | <0.001 | −401.67 |
| MYL1 | Myosin light chain 1 | <0.001 | <0.001 | −390.57 |
| H2AFJ | H2A histone family member J | <0.001 | <0.001 | −387.34 |
| HIST1H3I | Histone cluster 1 [3H] family member i | <0.001 | <0.001 | −331.21 |
| TGM3 | Transglutaminase 3 | <0.001 | <0.001 | −238.97 |
| PIK3C2G | Phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 γ | <0.001 | <0.001 | −229.54 |
| ZXDA | Zinc finger X-linked duplicated A | <0.001 | <0.001 | −211.53 |
| CDH19 | Cadherin 19 | <0.001 | <0.001 | −203.42 |
| MELTF | Melanotransferrin | <0.001 | <0.001 | −186.80 |
| TMEM47 | Transmembrane protein 47 | <0.001 | <0.001 | −162.18 |
| ARMCX2 | Armadillo repeat containing X-linked 2 | <0.001 | <0.001 | −158.24 |
| MAP10 | Microtubule associated protein 10 | <0.001 | <0.001 | −157.43 |
| COL22A1 | Collagen type XXII α 1 chain | <0.001 | <0.001 | −156.85 |
| HCK | HCK proto-oncogene, Src family tyrosine kinase | <0.001 | <0.001 | −151.10 |
| COL1A1 | Collagen type I α 1 chain | <0.001 | <0.001 | −146.07 |
| TOMM40L | Translocase of outer mitochondrial membrane 40–like | <0.001 | <0.001 | −139.23 |
Only protein-coding transcripts are shown.