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. 2018 Sep 5;6(2):196–202. doi: 10.14744/nci.2018.44977

TABLE 2.

Cardiovascular drugs withdrawn due to their adverse effects on the cardiovascular system

Medicinal product Class Reason for withdrawal
Prenylamine Antianginal Cardiovascular: multifactorial ventricular tachycardia
Adenosine phosphate Antiarrhythmic Cardiovascular
Bepridil Antiarrhythmic Cardiovascular
Dofetilide Antiarrhythmic Cardiovascular
Encainide Antiarrhythmic Cardiovascular
Gallopamil Antiarrhythmic Not specified, cardiovascular
Hydrochlorothiazide+sotalol Antihypertensive Cardiovascular, drug interactions
Nifedipine (10mg) Antihypertensive Cardiovascular
Isoprenaline Cardiac stimulant Cardiovascular
Buflomedil Vasodilator Neurotoxicity, cardiotoxicity
Indoramin Vasodilator Cardiovascular
Naftidrofuryl oxalate (IV) Vasodilator Cardiovascular, immunologic, liver, urinary tract
Levarterenol Vasopressor Nervous, cardiovascular