Figure 2.

Cells increase IL11 upon acid bone lysate (ABL) coating of titanium. Turned and rough titanium discs were treated with ABL for 1 hour followed by three vigorous washes with buffered saline. Gingival fibroblasts were seeded onto the ABL coated titanium discs overnight with and without SB431542, the inhibitor for the TGF‐β RI kinase. A, Reverse transcription PCR analysis and B, immunoassays were performed for IL11. N = 3‐5. Data represent the mean ± standard deviation relative to the control of independent experiments. Mann‐Whitney U test (A) and Kruskal‐Wallis test with Dunn's multiple comparisons correction (B) were performed. Significance is indicated by *P < 0.05