Table S2.
Multivariable analysis of predictors for major morbidity (Clavien-Dindo Grade ≥III complications)a
| Estimated factors | Odds ratio | 95% CI | P-value |
|---|---|---|---|
| Age (year) (per 1-year increase) | 0.992 | 0.97–1.02 | 0.53 |
| Gender (male vs female) | 1.45 | 0.83–2.54 | 0.20 |
| Body mass index (kg/m2) (per unit decrease) | 1.07 | 1.005–1.14 | 0.036 |
| FEV1% (per unit decrease) | 1.01 | 0.994–1.03 | 0.19 |
| FEV1/FVC (%) (per unit decrease) | 1.02 | 0.98–1.05 | 0.34 |
| Systemic inflammation score (2 vs 0-1) | 1.87 | 1.09–3.20 | 0.023 |
| Neutrophil-to-lymphocyte ratio (per unit increase) | 0.92 | 0.79–1.08 | 0.29 |
| Platelet-to-lymphocyte ratio (per unit increase) | 1.006 | 1.001–1.01 | 0.017 |
| Smoking history | 1.44 | 0.79–2.63 | 0.23 |
| Respiratory comorbidity | 3.37 | 2.19–5.19 | <0.001 |
| Cardio-cerebrovascular comorbidity | 1.58 | 1.01–2.45 | 0.044 |
| Renal insufficiency | 1.17 | 0.60–2.27 | 0.64 |
| Pulmonary fissure completeness (incomplete vs complete) | 2.40 | 1.58–3.66 | <0.001 |
| Dense pleural adhesion (present vs absent) | 1.12 | 0.58–2.15 | 0.75 |
| Operation time (mins) (per 10 mins increase) | 1.02 | 1.01–1.03 | <0.001 |
| Estimated intraoperative blood loss (mL) (per 10 mL increase) | 1.001 | 0.998–1.003 | 0.67 |
| Tumor invasion (T2-3 vs T1) | 1.12 | 0.73–1.72 | 0.60 |
| Lymph node metastasis | 1.27 | 0.55–2.95 | 0.57 |
Notes: aThe multivariable logistic-regression model was established based on 152 patients with major morbidity and 706 patients without any morbidity to identify the risk factors for major morbidity. The data for minor morbidity (Clavien-Dindo Grade II complications) were excluded. This multivariable logistic-regression model got a Hosmer–Lemeshow P=0.10 and a C-statistic of 0.82 (95% CI: 0.78-0.85; P<0.001). FEV1/FVC, FEV1 to FVC ratio.