Table 1.
Receiver operator characteristic curve analysis for four-gene panel and four genes separately to etoposide resistance status in small-cell lung cancer cell lines
| Gene | Area under curve | 95% confidence interval | Sensitivity | Specificity | Youden index | P-value |
|---|---|---|---|---|---|---|
| CSMD3 | 0.697 | 0.546–0.848 | 0.600 | 0.794 | 0.394 | 0.016 |
| PCLO | 0.591 | 0.429–0.754 | 0.300 | 0.882 | 0.182 | 0.267 |
| RYR1 | 0.631 | 0.469–0.792 | 0.350 | 0.912 | 0.262 | 0.111 |
| EPB41L3 | 0.610 | 0.447–0.774 | 0.250 | 0.971 | 0.221 | 0.179 |
| Panel | 0.804 | 0.679–0.930 | 0.850 | 0.706 | 0.556 | <0.001 |