Table 1.
Patient and tumour characteristics
| Hospital 1 (n = 32) | Hospital 2 (n = 19) | Total (n = 51) | |
|---|---|---|---|
| Age (years) * | 64 (53–72) | 64 (60–68) | 64 (56–72) |
| Sex ratio (M : F) | 23 : 9 | 16 : 3 | 39 : 12 |
| Tumour location | |||
| Upper oesophageal | 0 | 1 | 1 (2) |
| Middle oesophageal | 3 | 3 | 6 (12) |
| Lower oesophageal | 15 | 11 | 26 (51) |
| Gastro‐oesophageal junction | 14 | 4 | 18 (35) |
| Histological tumour type | |||
| Adenocarcinoma | 28 | 14 | 42 (82) |
| Squamous cell carcinoma | 4 | 5 | 9 (18) |
| Grade of differentiation | |||
| Well differentiated | 2 | 0 | 2 (4) |
| Moderately differentiated | 15 | 10 | 25 (49) |
| Poorly differentiated | 14 | 3 | 17 (33) |
| Undifferentiated | 0 | 2 | 2 (4) |
| Unknown | 1 | 4 | 5 (10) |
| Clinical T category † | |||
| cT1 | 1 | 0 | 1 (2) |
| cT2 | 8 | 4 | 12 (24) |
| cT3 | 23 | 14 | 37 (73) |
| cT4a | 0 | 1 | 1 (2) |
| Clinical N category † | |||
| cN0 | 15 | 4 | 19 (37) |
| cN1 | 6 | 8 | 14 (27) |
| cN2 | 9 | 7 | 16 (31) |
| cN3 | 2 | 0 | 2 (4) |
| Radicality of resection | |||
| R0 | 32 | 18 | 50 (98) |
| R1 | 0 | 1 | 1 (2) |
| Mandard grade | |||
| TRG 1 | 6 | 6 | 12 (24) |
| TRG 2 | 10 | 7 | 17 (33) |
| TRG 3 | 12 | 4 | 16 (31) |
| TRG 4 | 3 | 1 | 4 (8) |
| TRG 5 | 1 | 1 | 2 (4) |
Values in parentheses are percentages unless indicated otherwise;
*
values are median (i.q.r.).
†
According to the seventh edition of the TNM classification32. Hospital 1, Netherlands Cancer Institute; hospital 2, University Medical Center Utrecht. TRG, tumour regression grade.