Table 3.
PFS | OS | |||
---|---|---|---|---|
HR (95% CI) | P-value | HR (95% CI) | P-value | |
TP53 mutation | 0.03* | 0.017* | ||
Wt | 1 | 1 | ||
Mut | 1.87(1.06–3.29) | 2.73(1.20–6.21) | ||
EGFR mutation | 0.032* | 0.002* | ||
Del19/L858R | 1 | 1 | ||
Other mutation | 1.98(1.06–3.70) | 3.58(1.61–7.94) | ||
Line of therapy | 0.017* | 0.825 | ||
First line | 1 | 1 | ||
Non-first line | 2.02(1.14–3.58) | 1.09(0.51–2.32) |
Note: *P<0.05.
Abbreviations: NSCLC, non-small-cell lung cancer; PFS, progression-free survival; OS, overall survival