Table 1.

The Bulk (Average Along the Whole Cartilage Thickness) Partitions of CA4+ (Iodine) and Gadoteridol (Gadolinium) in Articular Cartilage at 1, 2, 24, 48, and 72 h After the Contrast Agent Immersion, Optical Densities (i.e., Proteoglycan Content), and Mankin Scores for Cartilage Samples from Different Anatomical Sites

	Contrast agent partition (%) (normalized partition for CA4 +)
	1 h		2 h		24 h		48 h		72 h
Location	CA4+	Gadoteridol	CA4+	Gadoteridol	CA4+	Gadoteridol	CA4+	Gadoteridol	CA4+	Gadoteridol	Optical density	Mankin score
FLC	110 ± 20	44 ± 8	142 ± 15	51 ± 6	324 ± 61	64 ± 3	386 ± 76	66 ± 7	422 ± 84	67 ± 5	0.85 ± 0.19	4.86 ± 2.14
(n = 8)	(261 ± 74)		(289 ± 51)		(511 ± 112)		(602 ± 162)		(649 ± 172)
FMC	120 ± 16	46 ± 10	152 ± 23	53 ± 9	376 ± 49	60 ± 6	428 ± 63	65 ± 4	439 ± 77	69 ± 8	0.87 ± 0.07	6.45 ± 1.99
(n = 7)	(292 ± 81)		(302 ± 79)		(642 ± 98)		(671 ± 109)		(652 ± 176)
FT	122 ± 18	42 ± 8	150 ± 12	53 ± 7	368 ± 62	61 ± 4	426 ± 108	62 ± 4	452 ± 113	63 ± 4	0.89 ± 0.20	4.96 ± 1.08
(n = 6)	(313 ± 90)		(289 ± 50)		(615 ± 136)		(709 ± 225)		(729 ± 189)
TLC	105 ± 29	43 ± 13	141 ± 33	50 ± 9	320 ± 60	65 ± 6	398 ± 88	65 ± 5	429 ± 91	65 ± 4	0.81 ± 0.21	5.77 ± 1.78
(n = 12)	(247 ± 79)		(290 ± 80)		(506 ± 120)		(639 ± 188)		(672 ± 155)
TMC	112 ± 37	44 ± 4	142 ± 39	53 ± 8	353 ± 85	62 ± 7	426 ± 87	63 ± 7	464 ± 91	62 ± 6	0.87 ± 0.15	6.62 ± 1.14
(n = 12)	(245 ± 93)		(273 ± 83)		(599 ± 222)		(700 ± 201)		(764 ± 176)
Total	112 ± 28	44 ± 9	144 ± 29	52 ± 8	345 ± 70	63 ± 6	412 ± 87	64 ± 6	442 ± 93	65 ± 6	0.85 ± 0.18	5.83 ± 1.81
(n = 45)	(265 ± 88)		(287 ± 73)		(567 ± 162)		(663 ± 187)		(697 ± 178)

FLC, femoral lateral condyle; FMC, femoral medial condyle; FT, femoral trochlea; TLC, tibial lateral condyle; TMC, tibial medial condyle.