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. 2019 Mar 7;82(1):62–83. doi: 10.1002/mrm.27696

Table 2.

T1 and T2 relaxation times measured for 17 metabolites and 20 chemical groups on 6 different biopsies: normal cerebral cortex (n = 2), oligodendroglioma (n = 2), glioblastoma (n = 2)

Biopsy T1 (s) Solution T1 (s) Biopsy T2 (s) Solution T2 (s) Biopsy CPMG signal loss Solution CPMG signal loss
Acetate_1.92ppm 2.49 ± 0.15 3.20 1.42 ± 0.05 2.61 0.23 ± 0.02 0.28
Alanine_1.48ppm 0.92 ± 0.02 1.05 0.70 ± 0.04 0.83 0.13 ± 0.01 0.12
Ascorbate_4.52ppm 1.17 ± 0.03 1.78 0.63 ± 0.07 1.47 0.16 ± 0.01 0.14
Choline_3.22ppm 1.27 ± 0.08 1.45 1.09 ± 0.06 1.15 0.11 ± 0.01 0.11
Creatine_3.94ppm 0.71 ± 0.03 0.80 0.57 ± 0.06 0.69 0.15 ± 0.01 0.13
Creatine_3.03ppm 1.34 ± 0.05 1.49 0.89 ± 0.06 1.22 0.14 ± 0.01 0.12
GABA_1.90ppm 0.83 ± 0.06 1.17 0.40 ± 0.06 0.92 0.21 ± 0.02 0.12
Glutamate_2.09ppm 0.68 ± 0.02 0.68 0.39 ± 0.02 0.58 0.21 ± 0.01 0.15
Glutamine_2.14ppm 0.62 ± 0.01 0.72 0.45 ± 0.02 0.58 0.19 ± 0.01 0.15
Glutamine_2.45ppm 0.72 ± 0.02 0.79 0.55 ± 0.03 0.64 0.16 ± 0.01 0.14
Glycerophosphocholine_3.24ppm 0.57 ± 0.03 0.59 0.50 ± 0.02 0.46 0.18 ± 0.01 0.19
Glycine_3.56ppm 1.49 ± 0.05 2.05 0.89 ± 0.12 1.85 0.15 ± 0.01 0.16
Lactate_1.33ppm 0.99 ± 0.05 1.15 0.65 ± 0.06 0.77 0.15 ± 0.01 0.13
Lactate_4.12ppm 1.68 ± 0.14 3.43 0.53 ± 0.05 0.57 0.23 ± 0.01 0.39
Myo‐Inositol_4.05ppm 0.83 ± 0.02 1.19 0.45 ± 0.02 0.92 0.19 ± 0.01 0.12
NAA_2.02ppm 1.02 ± 0.06 1.09 0.60 ± 0.05 0.76 0.16 ± 0.01 0.13
Phosphocholine_3.23ppm 0.62 ± 0.02 0.65 0.50 ± 0.02 0.53 0.17 ± 0.01 0.16
Taurine_3.42ppm 1.33 ± 0.09 1.64 0.81 ± 0.07 1.34 0.14 ± 0.01 0.13
Valine_1.04ppm 0.67 ± 0.06 0.68 0.52 ± 0.01 0.61 0.17 ± 0.00 0.14
Scyllo‐Inositol_3.34ppm 0.87 ± 0.02 1.40 0.53 ± 0.03 0.93 0.17 ± 0.01 0.14

The value of T1 and T2 for the pure metabolite is also reported. The last 2 columns show the signal loss expected during a CPMG experiment for the 17 metabolites in a biopsy and in a pure solution, taking into account both T1 and T2 effects.