Table 2.
Biopsy T1 (s) | Solution T1 (s) | Biopsy T2 (s) | Solution T2 (s) | Biopsy CPMG signal loss | Solution CPMG signal loss | |
---|---|---|---|---|---|---|
Acetate_1.92ppm | 2.49 ± 0.15 | 3.20 | 1.42 ± 0.05 | 2.61 | 0.23 ± 0.02 | 0.28 |
Alanine_1.48ppm | 0.92 ± 0.02 | 1.05 | 0.70 ± 0.04 | 0.83 | 0.13 ± 0.01 | 0.12 |
Ascorbate_4.52ppm | 1.17 ± 0.03 | 1.78 | 0.63 ± 0.07 | 1.47 | 0.16 ± 0.01 | 0.14 |
Choline_3.22ppm | 1.27 ± 0.08 | 1.45 | 1.09 ± 0.06 | 1.15 | 0.11 ± 0.01 | 0.11 |
Creatine_3.94ppm | 0.71 ± 0.03 | 0.80 | 0.57 ± 0.06 | 0.69 | 0.15 ± 0.01 | 0.13 |
Creatine_3.03ppm | 1.34 ± 0.05 | 1.49 | 0.89 ± 0.06 | 1.22 | 0.14 ± 0.01 | 0.12 |
GABA_1.90ppm | 0.83 ± 0.06 | 1.17 | 0.40 ± 0.06 | 0.92 | 0.21 ± 0.02 | 0.12 |
Glutamate_2.09ppm | 0.68 ± 0.02 | 0.68 | 0.39 ± 0.02 | 0.58 | 0.21 ± 0.01 | 0.15 |
Glutamine_2.14ppm | 0.62 ± 0.01 | 0.72 | 0.45 ± 0.02 | 0.58 | 0.19 ± 0.01 | 0.15 |
Glutamine_2.45ppm | 0.72 ± 0.02 | 0.79 | 0.55 ± 0.03 | 0.64 | 0.16 ± 0.01 | 0.14 |
Glycerophosphocholine_3.24ppm | 0.57 ± 0.03 | 0.59 | 0.50 ± 0.02 | 0.46 | 0.18 ± 0.01 | 0.19 |
Glycine_3.56ppm | 1.49 ± 0.05 | 2.05 | 0.89 ± 0.12 | 1.85 | 0.15 ± 0.01 | 0.16 |
Lactate_1.33ppm | 0.99 ± 0.05 | 1.15 | 0.65 ± 0.06 | 0.77 | 0.15 ± 0.01 | 0.13 |
Lactate_4.12ppm | 1.68 ± 0.14 | 3.43 | 0.53 ± 0.05 | 0.57 | 0.23 ± 0.01 | 0.39 |
Myo‐Inositol_4.05ppm | 0.83 ± 0.02 | 1.19 | 0.45 ± 0.02 | 0.92 | 0.19 ± 0.01 | 0.12 |
NAA_2.02ppm | 1.02 ± 0.06 | 1.09 | 0.60 ± 0.05 | 0.76 | 0.16 ± 0.01 | 0.13 |
Phosphocholine_3.23ppm | 0.62 ± 0.02 | 0.65 | 0.50 ± 0.02 | 0.53 | 0.17 ± 0.01 | 0.16 |
Taurine_3.42ppm | 1.33 ± 0.09 | 1.64 | 0.81 ± 0.07 | 1.34 | 0.14 ± 0.01 | 0.13 |
Valine_1.04ppm | 0.67 ± 0.06 | 0.68 | 0.52 ± 0.01 | 0.61 | 0.17 ± 0.00 | 0.14 |
Scyllo‐Inositol_3.34ppm | 0.87 ± 0.02 | 1.40 | 0.53 ± 0.03 | 0.93 | 0.17 ± 0.01 | 0.14 |
The value of T1 and T2 for the pure metabolite is also reported. The last 2 columns show the signal loss expected during a CPMG experiment for the 17 metabolites in a biopsy and in a pure solution, taking into account both T1 and T2 effects.