Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Mar 5;69(4):1719–1734. doi: 10.1002/hep.30365

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2018 The Authors. Hepatology published by Wiley Periodicals, Inc., on behalf of American Association for the Study of Liver Diseases.

This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.

PMC Copyright notice

Epithelial regeneration after 72 hours of ex vivo culture. (A‐C) Hematoxylin and eosin staining. Epithelial lining appeared at the luminal surface as well as at the basolateral surface (arrows). These epithelial patches are in proximity of PBG (arrowheads) suggesting newly formed epithelium driven from PBG to restore the uncovered surface at several sides throughout the tissue slice. (D) Epithelial lining at basolateral and luminal side of the bile duct slice appeared negative for calretinin, which is specific for mesothelium (arrows). (E) All cells lining the basolateral and luminal side of the bile duct slice expressed EpCAM, confirming that the (re)generated monolayers consisted of epithelial cells (arrows). (A) Original magnification ×5. (B,C) Original magnification ×20. (D,E) Original magnification ×15. Abbreviation: L, lumen.