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. Author manuscript; available in PMC: 2019 Jun 26.
Published in final edited form as: Nature. 2018 Jan 17;553(7689):501–505. doi: 10.1038/nature25010

Extended Data Figure 8 |. MAP kinase stimulation induced by WT FGF21 or by the FGF21WF mutant.

Extended Data Figure 8 |

L6 cells co-expressing β-Klotho and FGFR1c were stimulated with wild-type FGF21 (upper panel) or FGF21WF (lower panel) and phosphorylation levels of MAP kinase in cell lysates were monitored.